PT - JOURNAL ARTICLE AU - Diana Pimenta AU - Maria João Araújo AU - Rita Ortiga AU - Ana Luisa Vieira AU - Rui Rolo AU - Lurdes Ferreira TI - Predictive factors for readmission of patients with Acute Exacerbation of Chronic Obstructive Pulmonary Disease and respiratory failure AID - 10.1183/23120541.RFMVC-2020.40 DP - 2020 Feb 13 TA - ERJ Open Research PG - 40 VI - 6 IP - suppl 4 4099 - http://openres.ersjournals.com/content/6/suppl_4/40.short 4100 - http://openres.ersjournals.com/content/6/suppl_4/40.full SO - erjor2020 Feb 13; 6 AB - Introduction: Chronic Obstructive Pulmonary Disease(COPD)is the 3rd leading cause of death in the world and patients need multiple hospitalizations because of acute exacerbations(AECOPD). Non invasive ventilation(NIV)reduces in-hospital mortality and the need for intubation.Objective: To identify predictive factors for 3-month readmission in patients hospitalized with AECOPD and respiratory failure requiring NIV.Methods: Retrospective analysis of patients hospitalized with AECOPD and respiratory failure under NIV between2015-2019.Descriptive data analysis was performed and the predictors of readmission at 3 months were identified.Results: A sample of 179patients was obtained,52.5% male,mean age78 ± 11 years.Most patients had more than one exacerbation in the previous year.Regarding chronic respiratory failure, 47.5% had home oxygen therapy(OT)and25.1% had NIV before hospitalization.The average time of NIV during hospitalization was 10 ± 7days.At discharge,49.2% and 46.4% of patients required OT and NIV,respectively.In respect to readmissions,26.3%patients were readmitted and 19% patients died.A statistically significant relationship was found between the blood gas values (pH and paCO2 at admission and pH,paCO2,HCO3 and lactates at discharge)and the need for readmission at 3months (p <0.05).Patients discharged without OT or NIV had a statistically significant relationship with readmission at 3 months(p <0.05).Conclusion: Gasometric results at admission and discharge were predictive factors for readmission at 3 months. Patients discharged without NIV and/or OT had a higher risk of early readmission.FootnotesCite this article as: ERJ Open Research 2020; 6: Suppl. 4, 40.This is an ERS Respiratory Failure and Mechanical Ventilation Conference abstract. No full-text version is available. Further material to accompany this abstract may be available at www.ers-education.org (ERS member access only).