RT Journal Article SR Electronic T1 Predictive factors for readmission of patients with Acute Exacerbation of Chronic Obstructive Pulmonary Disease and respiratory failure JF ERJ Open Research JO erjor FD European Respiratory Society SP 40 DO 10.1183/23120541.RFMVC-2020.40 VO 6 IS suppl 4 A1 Diana Pimenta A1 Maria João Araújo A1 Rita Ortiga A1 Ana Luisa Vieira A1 Rui Rolo A1 Lurdes Ferreira YR 2020 UL http://openres.ersjournals.com/content/6/suppl_4/40.abstract AB Introduction: Chronic Obstructive Pulmonary Disease(COPD)is the 3rd leading cause of death in the world and patients need multiple hospitalizations because of acute exacerbations(AECOPD). Non invasive ventilation(NIV)reduces in-hospital mortality and the need for intubation.Objective: To identify predictive factors for 3-month readmission in patients hospitalized with AECOPD and respiratory failure requiring NIV.Methods: Retrospective analysis of patients hospitalized with AECOPD and respiratory failure under NIV between2015-2019.Descriptive data analysis was performed and the predictors of readmission at 3 months were identified.Results: A sample of 179patients was obtained,52.5% male,mean age78 ± 11 years.Most patients had more than one exacerbation in the previous year.Regarding chronic respiratory failure, 47.5% had home oxygen therapy(OT)and25.1% had NIV before hospitalization.The average time of NIV during hospitalization was 10 ± 7days.At discharge,49.2% and 46.4% of patients required OT and NIV,respectively.In respect to readmissions,26.3%patients were readmitted and 19% patients died.A statistically significant relationship was found between the blood gas values (pH and paCO2 at admission and pH,paCO2,HCO3 and lactates at discharge)and the need for readmission at 3months (p <0.05).Patients discharged without OT or NIV had a statistically significant relationship with readmission at 3 months(p <0.05).Conclusion: Gasometric results at admission and discharge were predictive factors for readmission at 3 months. Patients discharged without NIV and/or OT had a higher risk of early readmission.FootnotesCite this article as: ERJ Open Research 2020; 6: Suppl. 4, 40.This is an ERS Respiratory Failure and Mechanical Ventilation Conference abstract. No full-text version is available. Further material to accompany this abstract may be available at www.ers-education.org (ERS member access only).