RT Journal Article
SR Electronic
T1 The utility of esophageal pressure measurement in acute hypercapnic respiratory failure due to severe COPD exacerbation requiring NIV
JF ERJ Open Research
JO erjor
FD European Respiratory Society
SP 18
DO 10.1183/23120541.RFMVC-2020.18
VO 6
IS suppl 4
A1 Alexandru Tudor Steriade
A1 Mihai Gologanu
A1 Daniela Necula
A1 Nicoleta Sargarovschi
A1 Diana Radu
A1 Diana Ionita
A1 Cornelia Tudose
A1 Dragos Bumbacea
YR 2020
UL http://openres.ersjournals.com/content/6/suppl_4/18.abstract
AB Introduction: Improving patient-ventilator interaction during mechanical ventilation with acute hypercapnic respiratory failure (AHRF) reduces mortality. The esophageal pressure (Pes) measurement is an established way of detecting asynchronies in mechanically ventilated patients. This study aimed to evaluate the potential of Pes measurement in detecting patient-ventilator asynchronies in patients with AHRF due to severe COPD exacerbation requiring NIV.Methods: A prospective cohort study was undertaken in a respiratory intermediate care unit in an academic medical center between 2018 and 2019. Pes and ventilator pressure (Paw) curves and other data were recorded. The signal analysis comprised of artifact elimination and measurement of the phase difference between Pes and Paw curves. The objective was to assess the potential of using the phase difference value as an indicator of asynchrony.Results: 15 patients (8 males, mean age 65 years) with severe COPD exacerbation with AHRF requiring NIV were included. All patients were successfully managed with NIV. Patient-ventilator asynchrony was clinically detected in 3 patients at admission. The signal analysis identified all episodes of asynchrony with phase difference values of 10-15° during asynchrony and value of 170-180° during synchrony period for the same patient.Conclusion: Pes measurement can be used to detect patient-ventilator asynchronies in severe COPD exacerbation with AHRF that requires NIV.FootnotesCite this article as: ERJ Open Research 2020; 6: Suppl. 4, 18.This is an ERS Respiratory Failure and Mechanical Ventilation Conference abstract. No full-text version is available. Further material to accompany this abstract may be available at www.ers-education.org (ERS member access only).