TY - JOUR T1 - Measurement validity of an electronic inspiratory loading device during inspiratory muscle training in weaning failure patients> JF - ERJ Open Research JO - erjor DO - 10.1183/23120541.RFMVC-2020.16 VL - 6 IS - suppl 4 SP - 16 AU - Marine Van Hollebeke AU - Diego Poddighe AU - Beatrix Clerckx AU - Greet Hermans AU - Rik Gosselink AU - Daniel Langer Y1 - 2020/02/13 UR - http://openres.ersjournals.com/content/6/suppl_4/16.abstract N2 - Introduction: A recently introduced electronic inspiratory loading device (EILD) provides valid information on breathing characteristics in COPD patients. This has not yet been confirmed in weaning failure patients.Aim: To investigate the measurement validity of this EILD. Method: In 30 patients, 64 training sessions were analysed. Flow and pressure signals of 2594 breaths, against a mean resistance of 24% of the maximal inspiratory pressure, were sampled and processed by the EILD (POWERbreathe KH2, HaB International,UK) and a pulmonary function device (Pocket-Spiro USB/BT 100, M.E.C) which served as gold standard.Result: Small but significant differences in median? breathing characteristics were observed between the devices (Table1). ICC’s were high and average bias small (range: -7to11%; Table1) indicating good to excellent agreement on a group level. However, the EILD missed ~6% of the breaths that could be recorded with the golden standard (fig1.). These missed breaths had significantly lower tidal volume (median: 0,07L) and lower mean inspiratory flow (median 0,12L/s; fig.2).Conclusion: EILD provides valid estimates of breathing characteristics to quantify the load during inspiratory muscle training in weaning failure patients. However, breaths with a very low tidal volume and/or mean inspiratory flow might not always be recorded with the inspiratory loading device.FootnotesCite this article as: ERJ Open Research 2020; 6: Suppl. 4, 16.This is an ERS Respiratory Failure and Mechanical Ventilation Conference abstract. No full-text version is available. Further material to accompany this abstract may be available at www.ers-education.org (ERS member access only). ER -