@article {Barut{\c c}u29, author = {Halime Sinem Barut{\c c}u and Ece Alt{\i}nay and Halide O{\u g}u{\c s} and Mine G{\"u}lden Polat}, title = {Comparison of AVAPS and BIPAP modes in patients with postoperative hypercapnic respiratory failure after open heart surgery}, volume = {6}, number = {suppl 4}, elocation-id = {29}, year = {2020}, doi = {10.1183/23120541.RFMVC-2020.29}, publisher = {European Respiratory Society}, abstract = {Purpose: The aim of this study was compare with the acute phase response of BIPAP and AVAPS which are two of the noninvasive mechanical ventilation modalities used in patients with hypercapnic respiratory failure after open heart surgery in the early period.Materials and Methods: 13 women (38.2\%) and 21 men (61.8\%) with a mean age of 61.14{\textpm}11.22 years who had acute hypercapnic respiratory failure were included in the study. The patients were randomized and divided into BIPAP and AVAPS groups.The arterial blood gas data and vital signs of the patients before NIMV (noninvasive mechanical ventilation) were recorded. The NIMV mode initial data set to be EPAP 5 cmH2O, IPAP 15 cmH2O and the pressure values were changed so that the target volume was 6-8 mL/kg (Vt). Starting FiO2~value was started with 40\% and saturation levels were aimed to be more than 92\%. After NIMV for one hour, the arterials bloods gas data and vital signs were recorded again.Results: There was a significiant difference in the arterials blood gas data pH, PCO2,~sO2, cHCO3 and respiratory rate and SpO2~in the AVAPS mode groups (p\<0,05). In the group with BIPAP mode, there was a significiant difference in the arterials blood gas data; PCO2 and cLAC, vital signs; respiratory rate and SpO2 (p\<0,05). No difference were observed when intra-group differences were compared between two groups differences (p\>0,05).Conclusions: Both BIPAP and AVAPS modes are equally effective for treatment of acute hypercapnic respiratory failure after open heart surgery in the early postoperative period.FootnotesCite this article as: ERJ Open Research 2020; 6: Suppl. 4, 29.This is an ERS Respiratory Failure and Mechanical Ventilation Conference abstract. No full-text version is available. Further material to accompany this abstract may be available at www.ers-education.org (ERS member access only).}, URL = {https://openres.ersjournals.com/content/6/suppl_4/29}, eprint = {https://openres.ersjournals.com/content}, journal = {ERJ Open Research} }