TY - JOUR T1 - Radiation therapy for augmenting the efficacy of immunotherapy in advanced non-small cell lung cancer: a case-controlled study JF - ERJ Open Research JO - erjor DO - 10.1183/23120541.00189-2019 VL - 6 IS - 1 SP - 00189-2019 AU - Chinthaka B. Samaranayake AU - Elizabeth McCaffrey AU - John Coucher AU - Margot Lehman AU - G. Tao Mai AU - Michelle A. Murphy Y1 - 2020/01/01 UR - http://openres.ersjournals.com/content/6/1/00189-2019.abstract N2 - Nivolumab, a human IgG4 anti-PD1 monoclonal antibody, has been shown to have promising results in patients with advanced non-small cell lung cancer (NSCLC) [1, 2]. Despite the improved outcomes compared to chemotherapy, only ∼20% of patients had a sustained favourable response, which highlights the need to identify measures that can augment the efficacy of immunotherapy in NSCLC [3].This study investigated the effects of previous radiation therapy on outcomes from nivolumab in advanced NSCLC, and found that previous radiation therapy resulted in significantly higher survival in patients treated with nivolumab for advanced NSCLC http://bit.ly/3btOFSL ER -