PT - JOURNAL ARTICLE AU - Claudia C. Dobler AU - Maryam Hakim AU - Sidhartha Singh AU - Matthew Jennings AU - Grant Waterer AU - Frances L. Garden TI - Ability of the LACE index to predict 30-day hospital readmissions in patients with community-acquired pneumonia AID - 10.1183/23120541.00301-2019 DP - 2020 Apr 01 TA - ERJ Open Research PG - 00301-2019 VI - 6 IP - 2 4099 - http://openres.ersjournals.com/content/6/2/00301-2019.short 4100 - http://openres.ersjournals.com/content/6/2/00301-2019.full SO - erjor2020 Apr 01; 6 AB - Background and objective Hospital readmissions within 30 days are used as an indicator of quality of hospital care. We aimed to evaluate the ability of the LACE (Length of stay, Acuity of admission, Comorbidities based on Charlson comorbidity score and number of Emergency visits in the last 6 months) index to predict the risk of 30-day readmissions in patients hospitalised for community-acquired pneumonia (CAP).Methods In this retrospective cohort study a LACE index score was calculated for patients with a principal diagnosis of CAP admitted to a tertiary hospital in Sydney, Australia. The predictive ability of the LACE score for 30-day readmissions was assessed using receiver operator characteristic curves with C-statistic.Results Of 3996 patients admitted to hospital for CAP at least once, 8.0% (n=327) died in hospital and 14.6% (n=584) were readmitted within 30 days. 17.8% (113 of 636) of all 30-day readmissions were again due to CAP, followed by readmissions for chronic obstructive pulmonary disease, heart failure and chest pain. The LACE index had moderate discriminative ability to predict 30-day readmission (C-statistic=0.6395) but performed poorly for the prediction of 30-day readmissions due to CAP (C-statistic=0.5760).Conclusions The ability of the LACE index to predict all-cause 30-day hospital readmissions is comparable to more complex pneumonia-specific indices with moderate discrimination. For the prediction of 30-day readmissions due to CAP, the performance of the LACE index and modified risk prediction models using readily available variables (sex, age, specific comorbidities, after-hours, weekend, winter or summer admission) is insufficient.The LACE index is easy to use and its ability to predict all-cause 30-day hospital readmissions for patients hospitalised with community-acquired pneumonia is comparable to more complex pneumonia-specific indices with moderate discrimination https://bit.ly/2SYkxam