RT Journal Article
SR Electronic
T1 Stem Cells, Cell Therapies, and Bioengineering in Lung Biology and Disease 2019
JF ERJ Open Research
JO erjor
FD European Respiratory Society
SP 00123-2020
DO 10.1183/23120541.00123-2020
VO 6
IS 4
A1 Darcy E. Wagner
A1 Laertis Ikonomou
A1 Sarah E. Gilpin
A1 Chelsea M. Magin
A1 Fernanda Cruz
A1 Allison Greaney
A1 Mattias Magnusson
A1 Ya-Wen Chen
A1 Brian Davis
A1 Kim Vanuytsel
A1 Sara Rolandsson Enes
A1 Anna Krasnodembskaya
A1 Mareike Lehmann
A1 Gunilla Westergren-Thorsson
A1 John Stegmayr
A1 Hani N. Alsafadi
A1 Evan T. Hoffman
A1 Daniel J. Weiss
A1 Amy L. Ryan
YR 2020
UL http://openres.ersjournals.com/content/6/4/00123-2020.abstract
AB A workshop entitled “Stem Cells, Cell Therapies and Bioengineering in Lung Biology and Diseases” was hosted by the University of Vermont Larner College of Medicine in collaboration with the National Heart, Lung and Blood Institute, the Alpha-1 Foundation, the Cystic Fibrosis Foundation, the International Society for Cell and Gene Therapy and the Pulmonary Fibrosis Foundation. The event was held from July 15 to 18, 2019 at the University of Vermont, Burlington, Vermont. The objectives of the conference were to review and discuss the current status of the following active areas of research: 1) technological advancements in the analysis and visualisation of lung stem and progenitor cells; 2) evaluation of lung stem and progenitor cells in the context of their interactions with the niche; 3) progress toward the application and delivery of stem and progenitor cells for the treatment of lung diseases such as cystic fibrosis; 4) progress in induced pluripotent stem cell models and application for disease modelling; and 5) the emerging roles of cell therapy and extracellular vesicles in immunomodulation of the lung. This selection of topics represents some of the most dynamic research areas in which incredible progress continues to be made. The workshop also included active discussion on the regulation and commercialisation of regenerative medicine products and concluded with an open discussion to set priorities and recommendations for future research directions in basic and translation lung biology.This workshop report discusses recent advances in cell therapy and bioengineering approaches for repair and regeneration of diseased lungs https://bit.ly/2DqA8eu