TY - JOUR T1 - The risks of applying normative values in paediatric cardiopulmonary exercise testing: a case report JF - ERJ Open Research JO - erjor DO - 10.1183/23120541.00333-2020 VL - 6 IS - 4 SP - 00333-2020 AU - Jessica L. Waterfall AU - Paul Burns AU - Dawn Shackell AU - Joanna Pepke-Zaba AU - Katrina E. Oates AU - Karl P. Sylvester Y1 - 2020/10/01 UR - http://openres.ersjournals.com/content/6/4/00333-2020.abstract N2 - We present a clinical case that highlights an important issue surrounding the limitations of normative reference values (NRV) for the interpretation of cardiopulmonary exercise testing (CPET). The patients gave written consent for their anonymised data to be presented. At present, for CPET there are many NRV available from different authors for both adult and paediatric populations [1–3]. Nevertheless, there is no single NRV available that encompasses both adult, paediatric and adolescent populations [1]. We highlight these issues in a paediatric subject and the urgent requirement for standardised age- and sex-related reference values for CPET, akin to the global lung initiative reference values for lung function [4].A clinical case in a paediatric subject highlights the urgent requirement for cardiopulmonary exercise testing age-related reference values to be harmonised, to ensure appropriate clinical interpretation and patient management https://bit.ly/36WgOSO ER -