TY - JOUR T1 - The effect of physical activity on asthma incidence over 10 years: population-based study JF - ERJ Open Research JO - erjor DO - 10.1183/23120541.00970-2020 SP - 00970-2020 AU - Anne Melissa Russell AU - Shyamali Dharmage AU - Elaine Fuertes AU - Alessandro Marcon AU - Anne-Elie Carsin AU - Silvia Pascual Erquicia AU - Joachim Heinrich AU - Ane Johannessen AU - Michael J Abramson AU - Andre F.S. Amaral AU - Isa Cerveri AU - Pascal Demoly AU - Vanessa Garcia-Larsen AU - Deborah Jarvis AU - Jesus Martinez-Moratalla AU - Dennis Nowak AU - Leopoldo Palacios-Gomez AU - Giulia Squillacioti AU - Wasif Raza AU - Margareta Emtner AU - Judith Garcia-Aymerich Y1 - 2021/01/01 UR - http://openres.ersjournals.com/content/early/2021/01/14/23120541.00970-2020.abstract N2 - Asthma remains a common disease around the world, with global estimates indicating that 4.3% of adults have doctor diagnosed asthma [1]. Physical activity has been found to improve asthma outcomes in adult with asthma [2, 3]. While it has been hypothesised that physical activity could also reduce asthma incidence through a variety of mechanisms, studies to date have provided mixed results. Some studies find that physical activity reduces the incidence of asthma [4, 5], yet others find no evidence for a reduction in risk [6, 7]. These inconsistent findings could be partly attributed to variation in the definition of incident asthma, which is mostly restricted to self-reported asthma outcomes. In this analysis, we investigated the association between (frequency and duration of) vigorous physical activity and asthma incidence over 10 years, using the European Community Respiratory Health Survey (ECRHS), considering multiple asthma related outcomes in an initially asthma-free population.FootnotesThis manuscript has recently been accepted for publication in the ERJ Open Research. It is published here in its accepted form prior to copyediting and typesetting by our production team. After these production processes are complete and the authors have approved the resulting proofs, the article will move to the latest issue of the ERJOR online. Please open or download the PDF to view this article.Conflict of interest: Dr. Russell has nothing to disclose.Conflict of interest: Dr. Dharmage has nothing to disclose.Conflict of interest: Dr. Fuertes has nothing to disclose.Conflict of interest: Dr. Marcon has nothing to disclose.Conflict of interest: Dr. Carsin has nothing to disclose.Conflict of interest: Dr. Pascual Erquicia has nothing to disclose.Conflict of interest: Dr. Heinrich has nothing to disclose.Conflict of interest: Dr. Johannessen has nothing to disclose.Conflict of interest: Dr. Abramson has nothing to disclose.Conflict of interest: Dr. Amaral has nothing to disclose.Conflict of interest: Dr. Cerveri has nothing to disclose.Conflict of interest: P. Demoly reports board fees from Chiesi, IQVIA, Ménarini and Sanofi; board and speaker bureau fees from AstraZeneca, Bausch & Lomb and ThermoFisher Scientific; and speaker fees from Mylan and Novartis, all outside the submitted work.Conflict of interest: Dr. Garcia-Larsen has nothing to disclose.Conflict of interest: Dr. Jarvis has nothing to disclose.Conflict of interest: Dr. Martinez-Moratalla has nothing to disclose.Conflict of interest: Dr. Nowak has nothing to disclose.Conflict of interest: Dr. Palacios Gómez has nothing to disclose.Conflict of interest: Dr. Squillacioti has nothing to disclose.Conflict of interest: Dr. Raza has nothing to disclose.Conflict of interest: Dr. Emtner has nothing to disclose.Conflict of interest: Dr. Garcia-Aymerich has nothing to disclose. ER -