PT  - JOURNAL ARTICLE
AU  - Iyer, Aparna
AU  - Radonic, Teodora
AU  - Heukamp, Lukas C.
AU  - Thunnissen, Erik
AU  - Daniels, Johannes M.A.
TI  - Inflammatory myofibroblastic tumour of the central airways: treatment and molecular analysis
AID  - 10.1183/23120541.00151-2020
DP  - 2021 Jan 01
TA  - ERJ Open Research
PG  - 00151-2020
VI  - 7
IP  - 1
4099  - http://openres.ersjournals.com/content/7/1/00151-2020.short
4100  - http://openres.ersjournals.com/content/7/1/00151-2020.full
SO  - erjor2021 Jan 01; 7
AB  - Inflammatory myofibroblastic tumours (IMT) are a rare cause of endobronchial masses in adults. Surgery has been the mainstay of treatment of endobronchial IMTs, based on the potential for recurrence. Interventional pulmonology has emerged as a minimally invasive and lung function preserving modality in management of airway obstruction due to tumours. We present a series of three adult patients with IMT treated endobronchially with a short discussion on its potential role. We also discuss how molecular analysis of IMTs for mutations in genes such as ALK and ROS1 might provide insights into clinical behaviour and potential targetable therapy in advanced, unresectable and metastatic cases.Inflammatory myofibroblastic tumours in central airways: bronchoscopic treatment of a “not so pseudo-” tumour https://bit.ly/2KgPntq