TY - JOUR T1 - Inflammatory myofibroblastic tumour of the central airways: treatment and molecular analysis JF - ERJ Open Research JO - erjor DO - 10.1183/23120541.00151-2020 VL - 7 IS - 1 SP - 00151-2020 AU - Aparna Iyer AU - Teodora Radonic AU - Lukas C. Heukamp AU - Erik Thunnissen AU - Johannes M.A. Daniels Y1 - 2021/01/01 UR - http://openres.ersjournals.com/content/7/1/00151-2020.abstract N2 - Inflammatory myofibroblastic tumours (IMT) are a rare cause of endobronchial masses in adults. Surgery has been the mainstay of treatment of endobronchial IMTs, based on the potential for recurrence. Interventional pulmonology has emerged as a minimally invasive and lung function preserving modality in management of airway obstruction due to tumours. We present a series of three adult patients with IMT treated endobronchially with a short discussion on its potential role. We also discuss how molecular analysis of IMTs for mutations in genes such as ALK and ROS1 might provide insights into clinical behaviour and potential targetable therapy in advanced, unresectable and metastatic cases.Inflammatory myofibroblastic tumours in central airways: bronchoscopic treatment of a “not so pseudo-” tumour https://bit.ly/2KgPntq ER -