TY - JOUR T1 - The role of allergies(A)and tobacco exposure(T)in Obstructive Sleep Apnea Syndrome(OSAS)Type I/II(I/II)in children, and Sublingual Immunotherapy(SLIT)for the treatment of children with OSAS I/II with an Allergic Profile(AP) JF - ERJ Open Research JO - erjor DO - 10.1183/23120541.sleepandbreathing-2021.39 VL - 7 IS - suppl 7 SP - 39 AU - K Kefala AU - P Guerin Y1 - 2021/04/16 UR - http://openres.ersjournals.com/content/7/suppl_7/39.abstract N2 - Background: A and T role in OSAS is not clarified.Objectives:To describe the caracteristics of children with OSAS.Methods:Characterization of a cohort of children(2-16years(y))with clinical OSAS who performed outpatient polygraphy(PG)(cidelec/somnolter jawac) during 1.01.2018-30.08.2019.Results: View this table:View this table:Conclusions: OSAS AP seems to be differentiated from classic OSAS,may not improve with T/A removal alone and worsens if A+/-asthma are not treated properly.PG may have a role to check asthma control.OSAS AP should be evoked upon a)A clinical signs(A rhinitis,eczema)b)obesity,if asthma and A precede obesity c)no typical OSAS profile(long,adenoid face,retrognathy).OSAS AP seems to be an A sign of the allergic march.AP OSAS and residual nocturnal cough after T/A removal could be favored by T exposure.Dust mites A should be explored in AP OSAS I/II,even without Family A,when T exposure is evident.SLIT should be recommended for AP OSAS I/II when a respiratory A(MA) is identified and could help decrease CPAP need.FootnotesCite this article as ERJ Open Research 2021; 7: Suppl. 7, 39.This is an ERS Lung Science Conference abstract. No full-text version is available. Further material to accompany this abstract may be available at www.ers-education.org (ERS member access only). ER -