TY - JOUR T1 - A randomised trial of a web-based physical activity self-management intervention in COPD JF - ERJ Open Research JO - erjor DO - 10.1183/23120541.00158-2021 SP - 00158-2021 AU - Stephanie A. Robinson AU - J. Allen Cooper AU - Rebekah L. Goldstein AU - Madeline Polak AU - Paola N. Cruz Rivera AU - David R. Gagnon AU - Amber Samuelson AU - Sheila Moore AU - Reema Kadri AU - Caroline R. Richardson AU - Marilyn L. Moy Y1 - 2021/01/01 UR - http://openres.ersjournals.com/content/early/2021/06/17/23120541.00158-2021.abstract N2 - Improving exercise capacity is a primary objective in chronic obstructive pulmonary disease (COPD). Declines in exercise capacity result in reduced physical activity (PA) and health-related quality of life (HRQL). Self-management interventions can teach patients skills and behaviours to manage their disease. Technology-mediated interventions have the potential to provide easily accessible support for disease self-management. We evaluated the effectiveness of a web-based self-management intervention, focused on PA promotion, on exercise capacity in COPD. This 6-month randomised controlled trial (NCT02099799) enrolled 153 persons with COPD at two U.S. sites (VABoston, n=108; VABirmingham, n=45). Participants were allocated (1:1) to the web-based self-management intervention (PA promotion through personalised, progressive step-count goals, feedback, online COPD-related education, and social support via an online community), or usual care. The primary outcome was exercise capacity (6-min walk test distance [6 MWD]). Secondary outcomes included PA (daily steps per day), HRQL (St. George's Respiratory Questionnaire Total Score), dyspnoea, COPD-related knowledge, and social support. Change in step-count goals reflected intervention engagement. Participants were 69±7 years old, mean FEV1% predicted 61±21%. Change in 6 MWD did not differ between groups. Intervention participants improved daily step counts by an average of 1312 more than usual care (p<0.001). Groups did not differ on other secondary outcomes. VABirmingham participants were significantly more engaged with the intervention, although site did not modify the effect of the intervention on 6 MWD or secondary outcomes. The intervention did not improve exercise capacity, but improved PA at 6 months. Additional intervention modifications are needed to optimise its COPD self-management capabilities.FootnotesThis manuscript has recently been accepted for publication in the ERJ Open Research. It is published here in its accepted form prior to copyediting and typesetting by our production team. After these production processes are complete and the authors have approved the resulting proofs, the article will move to the latest issue of the ERJOR online. Please open or download the PDF to view this article.Conflict of interest: Dr. Stephanie Robinson has nothing to disclose.Conflict of interest: Dr. J. Allen Cooper has nothing to disclose.Conflict of interest: Rebekah Goldstein has nothing to disclose.Conflict of interest: Madeline Polak has nothing to disclose.Conflict of interest: Paola Cruz Rivera has nothing to disclose.Conflict of interest: Dr. David Gagnon has nothing to disclose.Conflict of interest: Amber Samuelson has nothing to disclose.Conflict of interest: Sheila Moore has nothing to disclose.Conflict of interest: Reema Kadri has nothing to disclose.Conflict of interest: Dr. Caroline Richardson has nothing to disclose.Conflict of interest: Dr. Marilyn Moy has nothing to disclose. ER -