TY - JOUR T1 - Vaping-induced metabolomic signatures in the circulation of mice are driven by device type, e-liquid, exposure duration and sex JF - ERJ Open Research JO - erjor DO - 10.1183/23120541.00229-2021 VL - 7 IS - 3 SP - 00229-2021 AU - Alexander Moshensky AU - Mulong Du AU - John Shin AU - Ira Advani AU - Deepti Gunge AU - Denzil Mathew AU - Rita Alkolla AU - Ashley Du AU - Christian Javier AU - Lauren Ma AU - Albert Tran AU - Nicholas Nguyen AU - Jarod Olay AU - Sedtavut Nilaad AU - Jeffrey Ding AU - Mahan Najhawan AU - Jeramie D. Watrous AU - Christine M. Bojanowksi AU - Mohit Jain AU - David C. Christiani AU - Laura E. Crotty Alexander Y1 - 2021/07/01 UR - http://openres.ersjournals.com/content/7/3/00229-2021.abstract N2 - Electronic (e)-cigarette devices have evolved rapidly since the modern version was introduced in 2007 [1, 2]. Inhalation of aerosols generated by these devices has been tied to multiple lung diseases, and diseases and pathology outside the lungs, while the underlying mechanisms driving e-cigarette-associated pathology remain unknown [3–7].Each type of vaping device (vape pen, box Mod and JUUL), as well as nicotine and flavourings, induces a disparate metabolite profile or signature, such that each device and liquid is likely to lead to its own set of health effects https://bit.ly/3eExKzi ER -