PT - JOURNAL ARTICLE AU - Anna Migliore Norweg AU - Anne Skamai AU - Simona C. Kwon AU - Jonathan Whiteson AU - Kyle MacDonald AU - Francois Haas AU - Eileen G. Collins AU - Roberta M. Goldring AU - Joan Reibman AU - Yinxiang Wu AU - Greg Sweeney AU - Alicia Pierre AU - Andrea B. Troxel AU - Linda Ehrlich-Jones AU - Naomi M. Simon TI - Acceptability of Capnography Assisted Respiratory Therapy (CART): a new mind-body intervention for chronic obstructive pulmonary disease AID - 10.1183/23120541.00256-2021 DP - 2021 Jan 01 TA - ERJ Open Research PG - 00256-2021 4099 - http://openres.ersjournals.com/content/early/2021/08/12/23120541.00256-2021.short 4100 - http://openres.ersjournals.com/content/early/2021/08/12/23120541.00256-2021.full AB - Dyspnea self-management is often suboptimal for patients with chronic obstructive pulmonary disease (COPD). Many patients with COPD experience chronic dyspnea as distressing and disabling, especially during physical activities. Breathing therapy is a behavioral intervention that targets reducing the distress and impact of dyspnea on exertion in daily living.Using a qualitative design, we conducted interviews with 14 patients after they participated in a novel mind-body breathing therapy intervention adjunct, capnography-assisted respiratory therapy (CART), combined with outpatient pulmonary rehabilitation. Comprehensive CART consisted of patient-centered biofeedback, tailored breathing exercises, home exercise program, and motivational interviewing counseling. We assessed participants’ perceptions and reported experiences to gauge the acceptability of CART and refine CART based on feedback. Constant comparative analysis was used to identify commonalities and themes.We identified three main themes relating to the acceptability and reported benefits of CART: (1) Self-regulating breathing; (2) Impact on health; and (3) Patient satisfaction. Our findings were used to refine and optimise CART (i.e., its intensity, timing, and format) for COPD. By addressing dysfunctional breathing behaviors and dysregulated interoception, CART offers a promising new paradigm for relieving dyspnea and related anxiety in patients with COPD.FootnotesThis manuscript has recently been accepted for publication in the ERJ Open Research. It is published here in its accepted form prior to copyediting and typesetting by our production team. After these production processes are complete and the authors have approved the resulting proofs, the article will move to the latest issue of the ERJOR online. Please open or download the PDF to view this article.Conflict of interests: Anna Migliore Norweg has nothing to disclose.Conflict of interests: Anne Skamai has nothing to disclose.Conflict of interests: S. Kwon declares grants fron the National Institute on Disability, Independent Living, and Rehabilitation Research.Conflict of interests: Jonathan Whiteson has nothing to disclose.Conflict of interests: Kyle MacDonald has nothing to disclose.Conflict of interests: Francois Haas has nothing to disclose.Conflict of interests: Eileen G. Collins has nothing to disclose.Conflict of interests: Roberta M. Goldring has nothing to disclose.Conflict of interests: Joan Reibman has nothing to disclose.Conflict of interests: Yinxiang Wu has nothing to disclose.Conflict of interests: Greg Sweeney has nothing to disclose.Conflict of interests: Alicia Pierre has nothing to disclose.Conflict of interests: Andrea B. Troxel has nothing to disclose.Conflict of interests: Linda Ehrlich-Jones has nothing to disclose.Conflict of interests: Naomi M. Simon has nothing to disclose.