TY - JOUR T1 - Computed tomography after severe COVID-19 pneumonia: findings at 6 months and beyond JF - ERJ Open Research JO - erjor DO - 10.1183/23120541.00488-2021 VL - 7 IS - 4 SP - 00488-2021 AU - Thibaud Poitevineau AU - Guillaume Chassagnon AU - Samir Bouam AU - Paul Jaubert AU - Chérifa Cheurfa AU - Lucile Regard AU - Emma Canniff AU - Anh Tuan Dinh-Xuan AU - Marie-Pierre Revel Y1 - 2021/10/01 UR - http://openres.ersjournals.com/content/7/4/00488-2021.abstract N2 - Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infects the alveolar epithelial cells causing coronavirus disease (COVID-19) pneumonia of varying severity [1, 2]. 15–30% of patients develop acute respiratory distress syndrome (ARDS) requiring hospitalisation in intensive care units (ICU) and mechanical ventilation [2, 3]. At 3 months, there are persisting computed tomography (CT) abnormalities in 17 to 91% of discharged COVID-19 patients [4–8], mainly consistent with an organising pneumonia (OP) pattern. These anomalies are more frequently reported in patients who were admitted to ICU [9]. Pulmonary fibrosis has been reported at autopsy of patients deceased from COVID-19 pneumonia, along with pulmonary microvascular thrombosis [10].Parenchymal bands and ground-glass opacities consistent with a pattern of late organising pneumonia are frequently observed 6 months after ICU admission for #COVID19, whereas fibrotic changes of limited extent are only observed in about 1/3 of patients https://bit.ly/2UGOsbr ER -