TY - JOUR T1 - Outcomes and Survival Following Lung Transplantation in Non-Cystic Fibrosis Bronchiectasis JF - ERJ Open Research JO - erjor DO - 10.1183/23120541.00607-2021 SP - 00607-2021 AU - Frederick Jung AU - Leonard Riley AU - Jorge Lascano Y1 - 2022/01/01 UR - http://openres.ersjournals.com/content/early/2022/01/06/23120541.00607-2021.abstract N2 - Disease-specific outcomes in patients with non-cystic fibrosis bronchiectasis following lung transplantation are not well described.We performed a retrospective analysis to describe outcomes in these patients. Patients with non-cystic fibrosis bronchiectasis who have undergone lung transplantation in the United States were identified using the Organ Procurement and Transplant Network database. Survival data were analyzed for the post-lung allocation score period with Kaplan-Meier curves, and a log-rank test was conducted to compare survival data between an age, gender, and activation date matched non-cystic fibrosis bronchiectasis cohort.Seven hundred twenty-one patients with non-cystic fibrosis bronchiectasis were listed for lung transplantation between March 1992 and September 2019. Four hundred seven patients received lung transplantation with a median age at listing of 47 years. The Kaplan-Meier survival analysis for lung transplantation recipient non-cystic fibrosis bronchiectasis patients during the post-lung allocation score period at 1, 5, and 10 years was 87%, 53%, and 16% respectively. The median survival time post-lung transplantation is 6.0 years (IQR: 2.3–11.9 years), which is similar to an aged and gender matched cohort (p=0. 86).This retrospective analysis demonstrates that median survival after lung transplantation in non-cystic fibrosis bronchiectasis was similar to other lung transplantation recipients over the study period. We suggest that the development of specific criteria for lung transplantation in non-cystic fibrosis bronchiectasis may improve patient selection and benefit a larger group of patients with this therapy.FootnotesThis manuscript has recently been accepted for publication in the ERJ Open Research. It is published here in its accepted form prior to copyediting and typesetting by our production team. After these production processes are complete and the authors have approved the resulting proofs, the article will move to the latest issue of the ERJOR online. Please open or download the PDF to view this article.Conflict of interest: Frederick Jung has nothing to disclose.Conflict of interest: Leonard Riley has nothing to disclose.Conflict of interest: Jorge Lascano has nothing to disclose. ER -