TY - JOUR T1 - Curvilinearity provides additional information to lung clearance index only in a minority of children with early cystic fibrosis lung disease JF - ERJ Open Research JO - erjor DO - 10.1183/23120541.00582-2021 VL - 8 IS - 2 SP - 00582-2021 AU - Samantha Irving AU - Katie Bayfield AU - Jane C. Davies AU - Andrew Bush Y1 - 2022/04/01 UR - http://openres.ersjournals.com/content/8/2/00582-2021.abstract N2 - Advances in technology and international consensus guidelines [1] make multiple breath washout (MBW) testing feasible in many settings, particularly in cystic fibrosis (CF) centres, and in paediatrics, as many children and young people with respiratory disease may have normal spirometry [2].Curvilinearity, as calculated from multiple-breath washout, is abnormal in a small number of children with cystic fibrosis when other tests are still normal https://bit.ly/3p9QAV4 ER -