PT - JOURNAL ARTICLE AU - Meriem Affes AU - Rym Khayati AU - Monia Attia AU - Amira Jamoussi AU - Ines Baccouche AU - Salma Kchaou AU - Jalila Ben Khelil AU - Henda Nèji AU - Saoussen Hantous TI - CT scan imaging in acute infectious infiltrative lung disease before the covid-19 era AID - 10.1183/23120541.LSC-2022.249 DP - 2022 Mar 10 TA - ERJ Open Research PG - 249 VI - 8 IP - suppl 8 4099 - http://openres.ersjournals.com/content/8/suppl_8/249.short 4100 - http://openres.ersjournals.com/content/8/suppl_8/249.full SO - erjor2022 Mar 10; 8 AB - Background: Acute infectious infiltrative lung disease (AIILD) is characterized by diffuse parenchymal lung involvement, affecting the interstitial sector and/or the distal airways.The purpose of our study was to evaluate the role of computed tomography (CT) in the etiological diagnosis of AIILD and in their management in intensive care unit (ICU).Methods: Retrospective study over a period of 5 years including patients admitted in the ICU for acute respiratory distress related to pulmonary infection with an infiltrative lung disease on CT scan.Results: Our study included 35 patients (20 men and 15 women). 12 patients were tobacco smoker. Fever was present in 28 cases (80%). Hyperleukocytosis has been noted in 10 patients, and lymphopenia in 20 cases (57%). 23 patients underwent bronchoalveolar lavage which showed a predominantly neutrophilic formula in 11 cases. Main etiologies were viral pneumonitis (n=11: 8 cases of Influenza A H1N1, 1 case of Influenza A H3N2, 1 cases of adenovirus and 1 case of enterorhinovirus), pneumocystosis (n=10), tuberculosis (n=5), legionellosis (n=3), Acinetobacter baumannii (n=2) and Haemophilus influenzae (n=1). The microorganism was not identified in 3 cases. The diagnosis of AIILD was made by the radiologist in 32/35 cases (91%). The viral origin has only been suggested in 3 cases. Pneumocystosis has been mentioned in the CT report in 8 out of 10 cases and tuberculosis has been suggested on the 5 CT scans.Conclusion: Elementary CT scan signs and their distribution integrated to anamnestic, clinical and paraclinical findings often contribute to suggest the diagnosis FootnotesCite this article as ERJ Open Research 2022; 8: Suppl. 8, 249.This article was presented at the 2022 ERS Lung Science Conference, in session “Poster Session 2”.This is an ERS Lung Science Conference abstract. No full-text version is available. Further material to accompany this abstract may be available at www.ers-education.org (ERS member access only).