TY - JOUR T1 - Nasal nitric oxide measurement variability to establish a standard for reliable results JF - ERJ Open Research JO - erjor DO - 10.1183/23120541.00028-2022 SP - 00028-2022 AU - Nicole Beydon Y1 - 2022/01/01 UR - http://openres.ersjournals.com/content/early/2022/05/19/23120541.00028-2022.abstract N2 - Nasal nitric oxide (nNO) measurement is a first line test used to increase the post-measurement probability of primary ciliary dyskinesia in subjects with symptoms consistent with this diagnosis [1]. The accuracy of nNO measurement is essential since it will orientate the work-up towards tests that are usually highly specialised and sometimes invasive tests. Accuracy of biological measures relies on the technical and on the biological variability. While the accuracy of NO analysers is known better for chemiluminescence devices (eg. <1 ppb with 1% linearity from 0.1 to 5000 ppb, CLD 88® Eco MedicsLTD) than for widely used electrochemical devicesFootnotesThis manuscript has recently been accepted for publication in the ERJ Open Research. It is published here in its accepted form prior to copyediting and typesetting by our production team. After these production processes are complete and the authors have approved the resulting proofs, the article will move to the latest issue of the ERJOR online. Please open or download the PDF to view this article. ER -