TY - JOUR T1 - Prevalence and burden of chronic cough in China: a national cross-sectional study JF - ERJ Open Research JO - erjor DO - 10.1183/23120541.00075-2022 VL - 8 IS - 3 SP - 00075-2022 AU - Kewu Huang AU - Xiaoying Gu AU - Ting Yang AU - Jianying Xu AU - Lan Yang AU - Jianping Zhao AU - Xiangyan Zhang AU - Chunxue Bai AU - Jian Kang AU - Pixin Ran AU - Huahao Shen AU - Fuqiang Wen AU - Yahong Chen AU - Tieying Sun AU - Guangliang Shan AU - Yingxiang Lin AU - Sinan Wu AU - Ruiying Wang AU - Zhihong Shi AU - Yongjian Xu AU - Xianwei Ye AU - Yuanlin Song AU - Qiuyue Wang AU - Yumin Zhou AU - Wen Li AU - Liren Ding AU - Chun Wan AU - Wanzhen Yao AU - Yanfei Guo AU - Fei Xiao AU - Yong Lu AU - Xiaoxia Peng AU - Dan Xiao AU - Xiaoning Bu AU - Hong Zhang AU - Xiaolei Zhang AU - Li An AU - Shu Zhang AU - Zhixin Cao AU - Qingyuan Zhan AU - Yuanhua Yang AU - Lirong Liang AU - Huaping Dai AU - Bin Cao AU - Jiang He AU - Kian Fan Chung AU - Chen Wang A2 - , Y1 - 2022/07/01 UR - http://openres.ersjournals.com/content/8/3/00075-2022.abstract N2 - Background Chronic cough is a common complaint, but there are no population-based data on its burden in China. We determined the prevalence of chronic cough and its impact on health status in adults stratified by sex, age and the diagnosis of COPD or the presence of small airway dysfunction (SAD).Methods A representative sample of 57 779 Chinese adults aged 20 years or older was recruited and pulmonary function test was measured. Chronic cough was defined as cough lasting for >3 months in each year. Quality of life was assessed by the 12-item Short Form Health Survey (SF-12), and self-reported history of hospital visits was recorded.Results Chronic cough was found in 3.6% (95% CI 3.1–4.1) of Chinese adults, 2.4% (95% CI 1.9–3.1) of those aged 20–49 years and 6.0% (95% CI 5.3–6.8) of those aged 50 years or older. Individuals with chronic cough had an impaired physical component summary (PCS) score of the SF-12 (p<0.0001) and more emergency visits (p=0.0042) and hospital admissions (p=0.0002). Furthermore, the impact of chronic cough on PCS score was more significant in those aged 50 years or older, or with COPD (p=0.0018 or 0.0002, respectively), with the impact on hospital admission being more significant in those with COPD or with SAD (p=0.0026 or 0.0065, respectively).Conclusions Chronic cough is prevalent in China and is associated with a poorer health status, especially in individuals aged 50 years or older and those with the diagnosis of COPD or SAD.In the general adult population in China, chronic cough is prevalent and associated with poorer health status, especially in individuals aged ≥50 years and those with COPD or small airway dysfunction https://bit.ly/3785LYZ ER -