TY - JOUR T1 - Investigation of the frequency of obstructive sleep apnea syndrome in patients with subclinical hypothyroidism JF - ERJ Open Research JO - erjor DO - 10.1183/23120541.00186-2022 SP - 00186-2022 AU - Aysegul Gencer AU - Ersan Atahan AU - Pinar Kadioglu AU - Birsen Mutlu Y1 - 2022/01/01 UR - http://openres.ersjournals.com/content/early/2022/07/28/23120541.00186-2022.abstract N2 - Background The aim of this study is to determine the frequency of Obstructive Sleep Apnea Syndrome (OSAS) in a study group with the diagnosis of subclinical hypothyroidism and in a control group without the diagnosis of subclinical hypothyroidism. This study compares these two groups in terms of demographic characteristics, chronic diseases, and especially polysomnographic data.Methods A total of 120 patients were included in this study. They consistedof 60 patients with newly diagnosed subclinical hypothyroidism, and a control group of 60 patients with normal thyroid functions. Demographic, anthropometric, polysomnography data, and Epworth sleepiness scale scores of the patients were recorded and compared.Results Any significant difference in the frequency and severity of OSAS was not detected. A significant difference was found in the oxygen desaturation index (ODI), the apnea-hypopnea index (AHI) in REM sleep, the AHI in supine sleep position, and the arousal index of the group experiencing subclinical hypothyroidism with OSAS.Conclusion This study showed that there was no increase in OSAS frequency in patients with subclinical hypothyroidism, but it demonstrated that the ODI and the arousal index were significantly increased in OSAS patients diagnosed with subclinical hypothyroidism. It is thought that the diagnosis and treatment of OSAS in these patients may be important in preventing cardiovascular complications.FootnotesThis manuscript has recently been accepted for publication in the ERJ Open Research. It is published here in its accepted form prior to copyediting and typesetting by our production team. After these production processes are complete and the authors have approved the resulting proofs, the article will move to the latest issue of the ERJOR online. Please open or download the PDF to view this article.Conflict of interests: Aysegul Gencer has nothing to disclose.Conflict of interests: Ersan Atahan has nothing to disclose.Conflict of interests: Pinar Kadioglu has nothing to disclose.Conflict of interests: Birsen Mutlu has nothing to disclose. ER -