TY - JOUR T1 - One-year mortality in lung cancer in France according to key time points of care pathways JF - ERJ Open Research JO - erjor DO - 10.1183/23120541.00157-2022 SP - 00157-2022 AU - Axelle Rivière AU - Anne Isabelle Lecuyer AU - Emeline Laurent AU - Carole Lefebvre AU - Thierry Lecomte AU - Elodie Olivier AU - Delphine Carmier AU - Laurent Plantier AU - Leslie Grammatico-Guillon Y1 - 2022/01/01 UR - http://openres.ersjournals.com/content/early/2022/09/01/23120541.00157-2022.abstract N2 - Background It is unclear whether delays in care affect prognosis of patients with lung cancer. The primary objective of this study was to describe the care pathway of patients diagnosed with lung cancer in a French region. Secondary objectives were to identify markers associated with 1) time from imaging to treatment, and 2) with one-year survival.Methods In a retrospective cohort study, clinical data from multidisciplinary team meetings (MTM) for all incident lung cancer cases discussed in 2018 in one French region were matched with medico-administrative data from the National Health Insurance Database. Care pathway time intervals were estimated for small cell lung cancer (SCLC), resected non-small cell lung cancer (NSCLC) and unresected NSCLC. Factors associated with delay in the care pathway were identified using linear regression; 1-year survival was analysed using Cox modelling.Results A total of 685 patients were included. Median time between imaging and treatment was 49 days (q1-q3: 33–73), and was lower in cases of metastatic disease, SCLC, and private care. At one year, 48% had died (resected NSCLC 12%). In unresected NSCLC, time from diagnostic imaging to first treatment <49 days was associated with a higher risk of death. Time intervals were similar in patients with squamous cell carcinoma versus adenocarcinoma or undifferentiated carcinoma.Discussion Time intervals in the care pathways of lung cancer were similar to previous reports, confirming the robustness of retrospective databases. In unresectable NSCLC, rapid care was not associated with better survival.FootnotesThis manuscript has recently been accepted for publication in the ERJ Open Research. It is published here in its accepted form prior to copyediting and typesetting by our production team. After these production processes are complete and the authors have approved the resulting proofs, the article will move to the latest issue of the ERJOR online. Please open or download the PDF to view this article.Conflict of interest: The authors declare that there is no conflict of interest. ER -