TY - JOUR T1 - End-tidal CO<sub>2</sub> partial pressure is a reliable surrogate of arterial CO<sub>2</sub> partial pressure across different O<sub>2</sub>, CO<sub>2</sub>, and barometric pressures JF - ERJ Open Research JO - erjor DO - 10.1183/23120541.00507-2022 SP - 00507-2022 AU - Giorgio Manferdelli AU - Benjamin J. Narang AU - Nicolas Bourdillon AU - Tadej Debevec AU - Grégoire P. Millet Y1 - 2023/01/01 UR - http://openres.ersjournals.com/content/early/2023/02/09/23120541.00507-2022.abstract N2 - Accurate measurement of arterial carbon dioxide partial pressure (PaCO2) is critical in emergency medicine as a marker of sufficient alveolar ventilation [1], and in human physiology to understand respiratory and cerebrovascular regulation [2]. The current gold standard technique to measure PaCO2 is through arterial catheterization and analysis of blood gasses, although arterialized capillary blood (e.g. earlobe or fingertip) is often used to alleviate the invasiveness and risk associated with arterial sampling [3]. In either case, direct measurement of blood gasses does not allow for continuous data recording.FootnotesThis manuscript has recently been accepted for publication in the ERJ Open Research. It is published here in its accepted form prior to copyediting and typesetting by our production team. After these production processes are complete and the authors have approved the resulting proofs, the article will move to the latest issue of the ERJOR online. Please open or download the PDF to view this article.Conflict of interest: No conflicts of interest, financial or otherwise, are declared by the authors. ER -