TY - JOUR T1 - NICE asthma guidelines: time to re-evaluate the diagnostic value of exercise challenge testing? JF - ERJ Open Research JO - erjor DO - 10.1183/23120541.00447-2022 VL - 9 IS - 2 SP - 00447-2022 AU - Andrew J. Simpson AU - Oliver J. Price Y1 - 2023/03/01 UR - http://openres.ersjournals.com/content/9/2/00447-2022.abstract N2 - Asthma is a heterogenous chronic inflammatory lower airways disease that affects >350 million of the global population [1]. It is now recognised that securing a diagnosis is often challenging given clinical examination can be normal at rest and symptoms have a broad differential diagnosis. In support of this concept, a seminal study by Aaron et al. [2] observed that almost one third of adults with a physician diagnosis showed no clinical or laboratory evidence of asthma when re-examined at 12 months. Similarly, underdiagnosis remains a widespread issue, with estimates ranging between 19% and 73%, depending on the diagnostic methods and population studied [3].NICE asthma diagnosis recommendations for the use of ECT are based on a limited number of studies that violate current ECT recommendations. Further research is therefore required to re-evaluate the diagnostic value of ECT. https://bit.ly/3iS4smw ER -