TY - JOUR T1 - Latent class analysis-based subgroups and response to corticosteroids in hospitalised community-acquired pneumonia patients: a validation study JF - ERJ Open Research JO - erjor DO - 10.1183/23120541.00577-2022 VL - 9 IS - 2 SP - 00577-2022 AU - Esther Wittermans AU - Philip A. van der Zee AU - Hongchao Qi AU - Jan C. Grutters AU - G. Paul Voorn AU - Willem Jan W. Bos AU - Ewoudt M.W. van de Garde AU - Henrik Endeman Y1 - 2023/03/01 UR - http://openres.ersjournals.com/content/9/2/00577-2022.abstract N2 - Latent class analysis (LCA), a statistical method to identify “hidden” subgroups within a population, has identified clinically distinct subgroups with treatment implications in acute respiratory distress syndrome and COVID-19 [1–3]. We recently showed that LCA could also identify two clinically distinct subgroups in community-acquired pneumonia (CAP) [4].In patients with community-acquired pneumonia, LCA can identify robust prognostic subgroups based on clinical and inflammatory parameters. Yet, these subgroups have not proven robust in predicting response to adjunctive dexamethasone treatment. https://bit.ly/3O5eaxz ER -