TY - JOUR T1 - Risk factors and interventions for developing recurrent pneumonia in older adults JF - ERJ Open Research JO - erjor DO - 10.1183/23120541.00516-2022 SP - 00516-2022 AU - Kazufumi Takada AU - Kazumasa Ogawa AU - Atsushi Miyamoto AU - Hiroshi Nakahama AU - Shuhei Moriguchi AU - Kyoko Murase AU - Shigeo Hanada AU - Hisashi Takaya AU - Meiyo Tamaoka AU - Daiya Takai Y1 - 2023/01/01 UR - http://openres.ersjournals.com/content/early/2023/03/23/23120541.00516-2022.abstract N2 - Pneumonia is common among older adults and often recurrent. Several studies have been conducted on the risk factors for pneumonia; however, little is known about the risk factors for recurrent pneumonia. This study aimed to identify the risk factors for developing recurrent pneumonia among older adults and to investigate methods of prevention.We analysed the data of 256 patients aged 75 years or older who were admitted for pneumonia between June 2014 and May 2017. Moreover, we reviewed the medical records for the subsequent 3 years and defined the readmission caused by pneumonia as recurrent pneumonia. Risk factors for recurrent pneumonia were analysed using multivariable logistic regression analysis. Differences in the recurrence rate based on the types and use of hypnotics were also evaluated.Of the 256 patients, 90 (35.2%) experienced recurrent pneumonia. A low body mass index (odds ratio [OR], 0.91; 95% confidence interval [CI]: 0.83‒0.99), history of pneumonia (OR: 2.71; 95% CI: 1.23‒6.13), lung disease as a comorbidity (OR: 4.73; 95% CI: 2.13‒11.60), taking hypnotics (OR: 2.16; 95% CI: 1.18‒4.01), and taking histamine-1 receptor antagonist (H1RA) (OR: 2.38; 95% CI: 1.07‒5.39) were risk factors. Patients taking benzodiazepine as hypnotics were more likely to experience recurrent pneumonia than patients not taking hypnotics (OR: 2.29; 95% CI: 1.25–4.18).We identified several risk factors for recurrent pneumonia. Among them, restricting the use of H1RA and hypnotics, in particular, benzodiazepines may be useful in preventing the recurrence of pneumonia in adults aged 75 years or older.FootnotesThis manuscript has recently been accepted for publication in the European Respiratory Journal. It is published here in its accepted form prior to copyediting and typesetting by our production team. After these production processes are complete and the authors have approved the resulting proofs, the article will move to the latest issue of the ERJ online. Please open or download the PDF to view this article.Conflict of interest: All authors have no conflict of interest to declare. ER -