RT Journal Article
SR Electronic
T1 Risk factors and interventions for developing recurrent pneumonia in older adults
JF ERJ Open Research
JO erjor
FD European Respiratory Society
SP 00516-2022
DO 10.1183/23120541.00516-2022
A1 Kazufumi Takada
A1 Kazumasa Ogawa
A1 Atsushi Miyamoto
A1 Hiroshi Nakahama
A1 Shuhei Moriguchi
A1 Kyoko Murase
A1 Shigeo Hanada
A1 Hisashi Takaya
A1 Meiyo Tamaoka
A1 Daiya Takai
YR 2023
UL http://openres.ersjournals.com/content/early/2023/03/23/23120541.00516-2022.abstract
AB Pneumonia is common among older adults and often recurrent. Several studies have been conducted on the risk factors for pneumonia; however, little is known about the risk factors for recurrent pneumonia. This study aimed to identify the risk factors for developing recurrent pneumonia among older adults and to investigate methods of prevention.We analysed the data of 256 patients aged 75 years or older who were admitted for pneumonia between June 2014 and May 2017. Moreover, we reviewed the medical records for the subsequent 3 years and defined the readmission caused by pneumonia as recurrent pneumonia. Risk factors for recurrent pneumonia were analysed using multivariable logistic regression analysis. Differences in the recurrence rate based on the types and use of hypnotics were also evaluated.Of the 256 patients, 90 (35.2%) experienced recurrent pneumonia. A low body mass index (odds ratio [OR], 0.91; 95% confidence interval [CI]: 0.83‒0.99), history of pneumonia (OR: 2.71; 95% CI: 1.23‒6.13), lung disease as a comorbidity (OR: 4.73; 95% CI: 2.13‒11.60), taking hypnotics (OR: 2.16; 95% CI: 1.18‒4.01), and taking histamine-1 receptor antagonist (H1RA) (OR: 2.38; 95% CI: 1.07‒5.39) were risk factors. Patients taking benzodiazepine as hypnotics were more likely to experience recurrent pneumonia than patients not taking hypnotics (OR: 2.29; 95% CI: 1.25–4.18).We identified several risk factors for recurrent pneumonia. Among them, restricting the use of H1RA and hypnotics, in particular, benzodiazepines may be useful in preventing the recurrence of pneumonia in adults aged 75 years or older.FootnotesThis manuscript has recently been accepted for publication in the European Respiratory Journal. It is published here in its accepted form prior to copyediting and typesetting by our production team. After these production processes are complete and the authors have approved the resulting proofs, the article will move to the latest issue of the ERJ online. Please open or download the PDF to view this article.Conflict of interest: All authors have no conflict of interest to declare.