Clinical profile of late-onset eosinophilic asthma patients

Adult onset of asthma
Equal distribution between sexes
Few or no allergies to common allergens
Elevated eosinophils in peripheral blood
At risk of severe exacerbations
Normal or moderately elevated IgE level
Low FEV1 and often persistent airflow limitation
Air trapping and dynamic hyperinflation
Chronic rhinosinusitis with nasal polyposis
Aspirin sensitivity
Good response to systemic corticosteroids
Good response to anti IL-5 treatment
  • FEV1: forced expiratory volume in 1 s; IL: interleukin.