TABLE 2

Software prediction of transcription factors binding to putative promoter of the leukotriene A4 hydrolase gene (LTA4H) containing particular single-nucleotide polymorphisms

Marker IDrs17025122rs7971150
Distances from ATG bp−4057−5381
AncestralGG
 Transcription factor binding sites1) Human acute myelogenous leukaemia factors

  • 1) cAMP-responsive element binding proteins

  • 2) PAR/bZIP family

  • 3) Cart-1

  • 4) LIM homeodomain factors

  • 5) PAX3 binding sites

  • 6) GC-box factors SP1/GC

SNPAA
 Transcription factor binding sites1) Human acute myelogenous leukaemia factors

  • 1) CLOX and CLOX homology (CDP) factors

  • 2) cAMP-responsive element binding proteins

  • 3) PAR/bZIP family

  • 4) Cart-1

  • 5) LIM homeodomain factors

  • 6) Fork head domain factors

  • 7) HOX transcription factors

  • 8) Paralogue HOX genes 1–8 from the four HOX clusters A–D

  • 9) Cart-1

  • 10) Paralogue HOX genes 1–8 from the four HOX clusters A–D

  • 11) CLOX and CLOX homology (CDP) factors

  • 12) GC-box factors SP1/GC

  • PAR/bZIP: proline- and acidic amino acid-rich basic leucine zipper; Cart-1: cartilage homeoprotein 1; PAX3: paired-box transcription factor 3; SP1: specificity protein 1; HOX: homeobox.