TABLE 3

Clinical parameters for patients with a positive UAT, stratified by antibiotic therapy

VariableAntibiotic therapy
No change (n=38)De-escalation (n=76)Targeted (n=20)
Age years58.5 (49.25–75)63 (50.5–74.25)57.5 (46.75–70.25)
Male18 (47.4)37 (48.7)10 (50)
Intensive care unit28 (73.7)48 (63.2)12 (60)
PaO2/FiO2217.2 (178.4–274.8)252.2 (204.9–303.8)303.8 (214.5–360.5)
Pleural effusion3 (7.9)12 (15.8)1 (5)
eCURB0.053 (0.023–0.162)0.04 (0.019–0.082)0.028 (0.015–0.054)
sCAP minor3 (2–3)2 (1–3)1 (0.75–2)
CURB-65 score
 06 (15.8)12 (15.8)7 (35)
 110 (26.3)25 (32.9)8 (40)
 216 (42.1)30 (39.5)5 (25)
 36 (15.8)7 (9.2)0
 402 (2.6)0
 5000
  • Data are presented as n (%) or median (interquartile range), unless otherwise stated. sCAP minor is the number of minor criteria for severe community-acquired pneumonia from the Infectious Diseases Society of America/American Thoracic Society 2007 community-acquired pneumonia guidelines 2007 and eCURB is the validated electronic version of CURB-65 (confusion, blood urea, respiratory rate, blood pressure, age 65 years) with weighted, continuous variables yielding a point estimate for 30-day mortality [13, 14]. PaO2: arterial oxygen tension; FiO2: fraction of inspired oxygen.