Clinical parameters for patients with a positive UAT, stratified by antibiotic therapy
Variable | Antibiotic therapy | ||
No change (n=38) | De-escalation (n=76) | Targeted (n=20) | |
Age years | 58.5 (49.25–75) | 63 (50.5–74.25) | 57.5 (46.75–70.25) |
Male | 18 (47.4) | 37 (48.7) | 10 (50) |
Intensive care unit | 28 (73.7) | 48 (63.2) | 12 (60) |
PaO2/FiO2 | 217.2 (178.4–274.8) | 252.2 (204.9–303.8) | 303.8 (214.5–360.5) |
Pleural effusion | 3 (7.9) | 12 (15.8) | 1 (5) |
eCURB | 0.053 (0.023–0.162) | 0.04 (0.019–0.082) | 0.028 (0.015–0.054) |
sCAP minor | 3 (2–3) | 2 (1–3) | 1 (0.75–2) |
CURB-65 score | |||
0 | 6 (15.8) | 12 (15.8) | 7 (35) |
1 | 10 (26.3) | 25 (32.9) | 8 (40) |
2 | 16 (42.1) | 30 (39.5) | 5 (25) |
3 | 6 (15.8) | 7 (9.2) | 0 |
4 | 0 | 2 (2.6) | 0 |
5 | 0 | 0 | 0 |
Data are presented as n (%) or median (interquartile range), unless otherwise stated. sCAP minor is the number of minor criteria for severe community-acquired pneumonia from the Infectious Diseases Society of America/American Thoracic Society 2007 community-acquired pneumonia guidelines 2007 and eCURB is the validated electronic version of CURB-65 (confusion, blood urea, respiratory rate, blood pressure, age 65 years) with weighted, continuous variables yielding a point estimate for 30-day mortality [13, 14]. PaO2: arterial oxygen tension; FiO2: fraction of inspired oxygen.