TABLE 1

Adherence of Pseudomonas aeruginosa TBCF121838 to cystic fibrosis (CF) buccal epithelial cells

SubjectsBound TBCF121838 bacteria per buccal epithelial cell
0–1010–2020–40>40
CF patients    
P. aeruginosa negative102
 <24 months P. aeruginosa positive72
 >36 months P. aeruginosa positive1#+1252
 Acute upper airway infection4
Non-CF controls    
 Healthy19
 Acute upper airway infection23
 Trypsinised buccal cells6
  • Data are presented as numbers of subjects. #: single patient of the cohort who chronically inhaled tobramycin; no P. aeruginosa had been detected in patient's sputum at the day of investigation. : single patient in this group classified as having a CF transmembrane conductance regulator-related disorder [8].