TABLE 1

Patient characteristics

Characteristic
Subjects n10
Male (%)7 (70)
Age years62±8
BMI kg·m−226.3±4.4
Fat-free mass % predicted109±14
Medication n
 LABA10
 LAMA10
 Theophyllin1
 ICS6
 Oral corticosteroids2
TLC % predicted142±16
RV % predicted245±83
FEV1 % predicted38±8
FEV1/FVC0.39±0.05
DLCO % predicted54±21
PaO2 mmHg67±7
PaCO2 mmHg38±2
Peak work rate W99±37
Peak work rate % predicted75±29
6MWD m454±101
6MWD % predicted68±16
Peak quadriceps force % predicted96±16
Peak hamstring force % predicted73±20
  • Data are presented as the mean±sd, unless otherwise indicated. BMI: body mass index; LABA: long-acting β2 agonists; LAMA: long-acting antimuscarinic agents; ICS: inhaled corticosteroids; TLC: total lung capacity; RV: residual volume; FEV1: forced expiratory volume in 1 s; FVC: forced vital capacity; DLCO: diffusing capacity factor of the lung for carbon monoxide; PaO2: arterial oxygen tension; PaCO2: arterial carbon dioxide tension; 6MWD: 6-min walk distance.