TABLE 4

Comparison of multidimensional indices with individual variables by received operating characteristic (ROC) analysis at 12 and 24 months

	12-month ROC c-statistic	p-value for comparison with FVC	24-month ROC c-statistic	p-value for comparison with FVC
Age	0.694	0.213	0.639	0.942
FVC	0.564	Ref.	0.645	Ref.
D_LCO	0.705	0.040	0.770	0.041
Walking distance	0.702	0.135	0.591	0.491
Lowest S_aO₂	0.669	0.212	0.638	0.922
CPI	0.657	0.037	0.761	0.013
GAP	0.636	0.115	0.722	0.091
DSP	0.729	0.073	0.623	0.785

FVC: forced vital capacity; D_LCO: diffusing capacity of the lung for carbon monoxide; S_aO₂: arterial oxygen saturation; CPI: Composite Physiological Index; GAP: Gender, Age, Physiology score; DSP: distance–saturation product; Ref.: reference.