TABLE 1

Characteristics of bronchiectasis patients with and without upper airway symptoms (UASs)

No UASsUASsp-value
Subjects12770
Female76 (61.4)49 (70.0)0.238
Age at onset years45.85±23.733.65±24.70.001
Current age years65.8±14.760.2±16.70.016
Time from onset to diagnosis years12.6 (3.7–27.5)23.8 (7.4–45.9)0.027
Aetiology#
 Presence of asthma7 (5.5)10 (14.3)0.036
 Idiopathic aetiology56 (44.1)34 (48.6)0.546
 COPD10 (7.9)2 (2.9)0.219
 Post-infectious aetiology37 (29.1)9 (12.9)0.010
 Gastro-oesophageal reflux01 (1.4)NA
 Radiation therapy6 (4.7)2 (2.9)NA
 Inflammatory bowel disease01 (1.4)NA
 Immune deficiency5 (3.9)5 (7.1)NA
 Rheumatoid arthritis3 (2.4)1 (1.4)NA
 Others/not completed evaluation3 (2.4)6 (8.5)NA
Eosinophils µL−1n=123
200 (100–280)
n=67
230 (100–400)
0.015
IgE IU·mL−1n=75
42 (11–119)
n=50
100 (11.8–328)
0.085
IgG IU·mL−1n=98
1160 (1005–1388)
n=62
1182 (945.3–1420)
0.944
FEV1 % predn=118
77.5±26.0
n=66
83.5±25.6
0.134
Chest CT Reiff scoren=109
7 (6–12)
n=56
6 (4–8.75)
0.031
Sinus CT Lund–Mackay scoren=61
2 (0–6)
n=45
9 (3.5–12.5)
<0.0001
Exacerbations per yearn=122
2 (1–4)
n=68
3 (2–4)
0.135
Occurrence of exacerbation in previous yearn=122
104 (85.2)
n=68
63 (92.6)
0.134

Data are presented as n, n (%), mean±sd or median (interquartile range), unless otherwise stated. COPD: chronic obstructive pulmonary disease; FEV1: forced expiratory volume in 1 s; CT: computed tomography; NA: not available. #: more than one aetiology may be present for some patients and therefore percentages exceed 100%. p<0.05 was considered significant.