TABLE 1

Patient characteristics

Subjects120
Age years52.61±14.0
Sex
 Male14 (11.7)
 Female106 (88.3)
Race
 White103 (85.8)
 Other17 (14.2)
  African-American/Black7 (5.8)
  Hispanic or Latino6 (5.0)
  Asian2 (1.7)
  Native American2 (1.7)
BMI
 Less than obese62 (51.7)
  Underweight (BMI <18.5 kg·m−2)2 (1.7)
  Healthy weight (BMI 18.5–24.9 kg·m−2)27 (22.5)
  Overweight (BMI 25.0–29.9 kg·m−2)33 (27.5)
 Obese (BMI ≥30 kg·m−2)58 (48.3)
WHO group I breakdown
 Idiopathic67 (55.8)
 Other53 (44.2)
  Connective tissue disease16 (13.3)
  Unknown13 (10.8)
  Congenital heart disease7 (5.8)
  Drug/toxin induced4 (3.3)
  Heritable3 (2.5)
  Idiopathic with heritable3 (2.5)
  Other7 (5.7)
NYHA Functional Class
 I/II81 (67.5)
  I11 (9.2)
  II70 (58.3)
 III/IV39 (32.5)
  III35 (29.2)
  IV4 (3.3)
Oxygen use63 (52.5)
Medications
 PGI28 (6.6)
 PDEI15 (12.5)
 ERA9 (7.5)
 PGI2+PDEI25 (20.8)
 PGI2+ERA7 (5.8)
 PDEI+ERA20 (16.7)
 PGI2+PDEI+ERA23 (19.2)

Data are presented as n, mean±sd or n (%). BMI: body mass index; WHO: World Health Organization; NYHA: New York Heart Association; PGI2: prostaglandin I2; PDEI: phosphodiesterase inhibitor; ERA: endothelin receptor antagonist.