Baseline lung functional characteristics of the study subjects

Severe asthmatic subjectsCOPD subjectsp-value
FEV1 % pred74±2273±220.89
FVC % pred89±1992±220.57
FEF25–75% % pred40±2135±160.23
FEF75% % pred53±2433±190.0007
FEF50% % pred41±2238±200.57
FEF25% % pred37±2147±230.10

Data are presented as mean±sd, unless otherwise stated. COPD: chronic obstructive pulmonary disease; FEV1: forced expiratory volume in 1 s; FVC: forced vital capacity; FEF: forced expiratory flow; FEF25–75%: FEF at 25–75% of FVC; FEF75%: FEF at 75% of FVC; FEF50%: FEF at 50% of FVC; FEF25%: FEF at 25% of FVC.