Inadequate initial antibiotic treatment |
Severely immunocompromised patients (neutropenia or stem cell transplant) |
Highly antibiotic-resistant pathogens |
Pseudomonas aeruginosa |
Carbapenem-resistant Acinetobacter spp. |
Carbapenem-resistant Enterobacteriaceae |
Second-line antibiotic treatment (e.g. colistin, tigecycline) |