Analysis | Healthy (n=20) | CF (n=20) | PCD (n=17) | |||
Mean±sd LCI2.5 | ΔLCI (95% CI) % | Mean±sd LCI2.5 | ΔLCI (95% CI) % | Mean±sd LCI2.5 | ΔLCI (95% CI) % | |
Standard | 7.11±0.45 | 10.13±1.98 | 10.12±2.21 | |||
Linear | 6.98±0.46*** | −2.0 (−2.7– −1.3) | 9.95±1.98*** | −2.0 (−2.4– −1.5) | 9.79±2.14*** | −1.1 (−1.9– −0.3) |
Fit-curve | 6.88±0.68*** | −3.6 (−6.4– 0.8) | 9.16±1.56*** | −9.7 (−12.4– −7.1) | 8.04±1.22*** | −19.7 (−29.8– −9.6) |
1st breath | 7.06±0.57 | −0.6 (−1.2– 0.0) | 9.99±1.90*** | −1.4 (−2.3–0.4) | 9.55±1.92*** | −5.1 (−6.0– −2.0) |
Cmean | 6.95±0.47*** | −2.5 (−3.6– −1.3) | 9.56±1.60*** | −5.4 (−7.2– −3.5) | 9.39±1.82*** | −5.1 (−7.4– −2.8) |
Cmedian | 6.94±0.47*** | −2.5 (−3.6– −1.5) | 9.61±1.60*** | −4.9 (−6.7– −3.1) | 9.49±2.68*** | −5.6 (−7.5– −2.7) |
CF: cystic fibrosis; PCD: primary ciliary dyskinesia; linear: linear interpolation method; fit-curve: fitting-curve method; 1st breath: LCI calculated at the first breath below a cut-off; Cmean: mean expiratory nitrogen concentration; Cmedian: median expiratory nitrogen concentration. ***: p<0.001, paired t-test compared with standard analysis.