Effect of response to physical activity promotion on change in chronic obstructive pulmonary disease (COPD) measures
| Change in COPD measure | Effect on change in COPD measure# (95% CI) | p-value |
| Daily step count | 2038 (1369–2708) | <0.0001 |
| FEV1 L¶ | 0.308 (0.0786–0.538) | 0.009 |
| FEV1 % pred | 10.63 (2.14–19.1) | 0.015 |
| 6MWT distance m | 43.6 (21.8–65.4) | 0.0002 |
| CRP mg·L−1 | −7.84 (−12.8– −2.89) | 0.0023 |
| IL-6 ng·mL−1 | −2.73 (−4.38– −1.08) | 0.002 |
| mMRC dyspnoea score | 0.154 (−0.0581–0.365) | 0.153 |
| BDI-II depression score | 0.0954 (−2.36–2.55) | 0.939 |
| SGRQ-TS | −3.52 (−8.79–1.76) | 0.188 |
FEV1: forced expiratory volume in 1 s; 6MWT: 6-min walk test; CRP: C-reactive protein; IL: interleukin; mMRC: modified Medical Research Council; BDI: Beck Depression Inventory; SGRQ-TS: St George's Respiratory Questionnaire-Total Score. #: effects on change in COPD measure are the model coefficients as determined by nine separate generalised linear regression models, adjusted for baseline COPD measure, physical activity promotion group, baseline daily step count, FEV1 % pred, body mass index, smoking status, history of depression, back pain, Medical Outcomes Study social support, season of enrolment, acute exacerbation during study, emergency room visit for pulmonary problem during study and pulmonary hospitalisation during study; ¶: model does not include FEV1 % pred. Responders/nonresponders is the independent variable (reference group=nonresponders); change in COPD measure (3-month minus baseline values) is the dependent variable.