TABLE 1

Exhaled nitric oxide fraction (FeNO) algorithm

FeNO concentration ppbICS dose changeACQ scoreβ2-agonist dose change
Level 1>29↑ 1 ICS step≤1.5No change
Level 216–29No change>1.5↑ 1 LABA step
Level 3<16↓ 1 ICS stepNA (FeNO >29 ppb)No change

ICS: inhaled corticosteroid; ACQ: Asthma Control Questionnaire; LABA: long-acting β2-agonist; NA: not applicable.