TABLE 3

Differences between preterm participants with and without expiratory flow limitation (EFL)

With EFLWithout EFL
Subjects n4561
BPD34 (76%)*30 (49%)
Male28 (62%)43 (70%)
Gestation PMA weeks27.0 (25.0–29.2)28.6 (25.3–30.2)
Mechanical ventilation days5.0 (1.3–30.1)2.0 (0.0–13.5)
CPAP days6.5 (1.0–24.9)5.6 (0.6–15.7)
Supplemental oxygen days74.0 (28.0–94.5)*22.0 (1.0–83.5)
FEV1 z-score−1.31±0.96*−0.12±0.83
FVC z-score−0.40 (−0.57–0.78)0.22 (−0.51–1.13)
FEV1/FVC z score−1.85±0.89*−0.71±0.83
VO2 peak L·min−11.54 (1.40–1.78)1.63 (1.42–1.86)
VO2 peak mL·kg·min−149.6 (43.2–52.3)47.5 (42.4–52.3)
Peak RQ1.03 (1.01–1.05)1.01 (0.99–1.02)
Maximum heart rate beats·min−1197 (187–207)195 (186–202)
VT L·kg−125 (22–28)25 (22–28)
fR breaths·min−162 (53–70)60 (52–69)
Maximum VE L·min−1·kg−11.55 (1.36–1.74)1.43 (1.30–1.67)
Breathing reserve %31.1 (26.4–35.6)35.5 (29.3–38.5)
Exercise symptoms21 (48%)23 (40%)
Docter diagnosed asthma ever23 (52%)*17 (29%)
Current asthma medication4 (9%)10 (17%)*

Data are presented as mean±sd, median (interquartile range) or n (%), unless otherwise stated. Not all children completed every question in the symptom questionnaire. BPD: bronchopulmonary dysplasia; PMA: postmenstrual age; CPAP: continuous positive airway pressure; FEV1: forced expiratory volume in 1 s; FVC: forced vital capacity; VO2: oxygen uptake; RQ: respiratory quotient; VT: tidal volume; fR: respiratory frequency; V′E: minute ventilation. *: p<0.05.