IDSA/ATS recommendations | ERS recommendations | |
Blood culture | Recommended in case of ICU admission, leukopenia, alcohol abuse, chronic severe liver disease, asplenia, positive pneumococcal urinary antigen test and presence of pleural effusion | Recommended in all patients hospitalised with CAP |
Sputum culture | Recommended in case of ICU admission, alcohol abuse, severe obstructive or structural lung disease, positive Legionella urinary antigen test, positive pneumococcal urinary antigen test and presence of pleural effusion | Recommended in case of purulent sputum sample |
Bronchoalveolar lavage culture | Recommended in case of intubation | Recommended in case of intubation |
Legionella urinary antigen test | Recommended in case of ICU admission, alcohol abuse and presence of pleural effusion | Recommended in all patients hospitalised with severe CAP |
Pneumococcal urinary antigen test | Recommended in case of ICU admission, leukopenia, alcohol abuse, chronic severe liver disease, asplenia and pleural effusion | Recommended in all patients hospitalised with severe CAP |
Acute-phase serology for Chlamydophila pneumoniae, Mycoplasma pneumoniae, and Legionella species | Not recommended | Not recommended |
ICU: intensive care unit; CAP: community-acquired pneumonia.