TABLE 1

Gene ontology (GO) biological processes altered in the airways with azithromycin treatment

GO biological processNumber of differentially expressed genesAdjusted p-value
Translational elongation281.25×10-17
Translation397.99×10-18
Immune response310.004
Energy coupled proton transmembrane transport, against electrochemical gradient50.012
Cellular macromolecule biosynthetic process740.016
Immune system processes360.017
Macromolecule biosynthetic process740.017
Antigen processing and presentation90.017
Actin filament-based process150.035
Antigen processing and presentation of peptide antigen60.042
Cellular biosynthetic process850.044