Multivariable analysis for the differences in the ratio of blood vessel volume in vessels <5 mm2 in cross-section (BV5) to total blood vessel volume (TBV) between subjects with lower-lobe bronchiectasis and without bronchiectasis
Cohort/subcohort | Difference in lower-lobe BV5/TBV | se | p-value |
Entire cohort | −1.5 | 0.35 | <0.0001 |
Emphysema status subcohort | |||
Subjects with emphysema | −1.8 | 0.52 | 0.0008 |
Subjects without emphysema | −1.6 | 0.46 | 0.0005 |
The differences in lower-lobe BV5/TBV×100 are from a multivariable regression model where the presence of lower lobes bronchiectasis is the main predictor. Analyses were adjusted for age, sex, race, pack-years smoked, forced expiratory volume in 1 s % predicted, total lung capacity determined by computed tomography % predicted, resting arterial oxygen saturation, percentage of low-attenuation areas below −950 Hounsfield units (%LAA−950) of the lower lobes and coronary artery disease. For the analysis stratified by emphysema of the lower lobes, %LAA−950 was omitted as a covariate.