TABLE 1

Demographic and clinical characteristics of the subjects by bronchiectasis status

Subjects without bronchiectasisSubjects with bronchiectasisp-value
Subjects331155
Age years60±964±9<0.0001
Females57%68%0.02
Non-Hispanic white race78%78%0.98
Height cm168±9166±80.009
Body mass index kg·m−229±629±60.86
Current smoking status41%37%0.33
Smoking history pack-years45±2545±230.93
Chronic heart failure1.8%0.7%0.44
Coronary artery disease10%15%0.12
FEV1 L2.2±0.82.0±0.80.006
FEV1 % predicted77±2477±260.73
FVC L3.3±0.93.0±0.90.002
FVC % predicted88±1788±190.84
TLCCT L5.5±1.45.3±1.20.29
TLCCT % predicted97±1799±140.32
6-min walk test distance m428±119403±1170.03
Resting SaO2 %96±396±30.32
Spirometric COPD47%50%0.52
Whole-lung TBV mL277±61275±590.68
Whole-lung BV5 mL167±41164±390.46
Whole-lung BV5/TBV %60±660±70.45
Whole-lung %LAA−950 %6.9±9.87.3±9.00.72
Upper-lobe %LAA−950 %7.8±10.87.9±9.30.90
Lower-lobe %LAA−950 %5.5±8.06.3±8.80.31

Data are presented as mean±sd, unless otherwise stated. Missing data: total lung capacity determined by computed tomography (TLCCT), n=4; TLCCT % predicted, n=4; 6-min walk test, n=2; whole-lung percentage of low-attenuation areas below −950 Hounsfield units (%LAA−950), n=4; %LAA−950 of the upper and lower lobes, n=4. FEV1: forced expiratory volume in 1 s; FVC: forced vital capacity; SaO2: arterial oxygen saturation; COPD: chronic obstructive pulmonary disease; TBV: total blood vessel volume; BV5: blood vessel volume in vessels <5 mm2 in cross-section.