Demographic and clinical characteristics of the subjects by bronchiectasis status
Subjects without bronchiectasis | Subjects with bronchiectasis | p-value | |
Subjects | 331 | 155 | |
Age years | 60±9 | 64±9 | <0.0001 |
Females | 57% | 68% | 0.02 |
Non-Hispanic white race | 78% | 78% | 0.98 |
Height cm | 168±9 | 166±8 | 0.009 |
Body mass index kg·m−2 | 29±6 | 29±6 | 0.86 |
Current smoking status | 41% | 37% | 0.33 |
Smoking history pack-years | 45±25 | 45±23 | 0.93 |
Chronic heart failure | 1.8% | 0.7% | 0.44 |
Coronary artery disease | 10% | 15% | 0.12 |
FEV1 L | 2.2±0.8 | 2.0±0.8 | 0.006 |
FEV1 % predicted | 77±24 | 77±26 | 0.73 |
FVC L | 3.3±0.9 | 3.0±0.9 | 0.002 |
FVC % predicted | 88±17 | 88±19 | 0.84 |
TLCCT L | 5.5±1.4 | 5.3±1.2 | 0.29 |
TLCCT % predicted | 97±17 | 99±14 | 0.32 |
6-min walk test distance m | 428±119 | 403±117 | 0.03 |
Resting SaO2 % | 96±3 | 96±3 | 0.32 |
Spirometric COPD | 47% | 50% | 0.52 |
Whole-lung TBV mL | 277±61 | 275±59 | 0.68 |
Whole-lung BV5 mL | 167±41 | 164±39 | 0.46 |
Whole-lung BV5/TBV % | 60±6 | 60±7 | 0.45 |
Whole-lung %LAA−950 % | 6.9±9.8 | 7.3±9.0 | 0.72 |
Upper-lobe %LAA−950 % | 7.8±10.8 | 7.9±9.3 | 0.90 |
Lower-lobe %LAA−950 % | 5.5±8.0 | 6.3±8.8 | 0.31 |
Data are presented as mean±sd, unless otherwise stated. Missing data: total lung capacity determined by computed tomography (TLCCT), n=4; TLCCT % predicted, n=4; 6-min walk test, n=2; whole-lung percentage of low-attenuation areas below −950 Hounsfield units (%LAA−950), n=4; %LAA−950 of the upper and lower lobes, n=4. FEV1: forced expiratory volume in 1 s; FVC: forced vital capacity; SaO2: arterial oxygen saturation; COPD: chronic obstructive pulmonary disease; TBV: total blood vessel volume; BV5: blood vessel volume in vessels <5 mm2 in cross-section.