Definition of a pulmonary exacerbation for children and adults with primary ciliary dyskinesia (PCD) participating in clinical research
Increased cough
Change in sputum volume and/or colour
Increased shortness of breath perceived by the patient or parent
Decision to start or change antibiotic treatment because of perceived pulmonary symptoms
Malaise, tiredness, fatigue or lethargy
New or increased haemoptysis
Temperature >38°C