Baseline demographics according to previous treatment
No previous COPD medication | Previous ICS only | Previous LABD only | Previous ICS/LABD | |
Subjects | 9423 | 643 | 1734 | 4617 |
Age years | 64.7 | 64.3 | 66.1 | 66.0 |
BMI kg·m−2 | 27.5 | 28.7 | 28.7 | 28.6 |
Females | 2325 (25%) | 201 (31%) | 429 (25%) | 1231 (27%) |
Former smokers | 4562 (48%) | 383 (60%) | 920 (53%) | 2900 (63%) |
Smoking pack-years | 40.0 | 37.8 | 43.6 | 41.5 |
Screening FEV1 % predicted | 60.1 | 59.0 | 59.8 | 58.7 |
One or more exacerbations | 3150 (33%) | 416 (65%) | 618 (36%) | 2258 (49%) |
Region | ||||
USA | 1469 (16%) | 63 (10%) | 218 (13%) | 803 (17%) |
Asia# | 1961 (21%) | 35 (5%) | 121 (7%) | 561 (12%) |
Europe 1¶ | 2139 (23%) | 88 (14%) | 1175 (68%) | 1872 (41%) |
Europe 2+ | 3076 (33%) | 352 (55%) | 172 (10%) | 1025 (22%) |
RoW§ | 778 (8%) | 105 (16%) | 48 (3%) | 356 (8%) |
Data are presented as mean, unless otherwise stated. COPD: chronic obstructive pulmonary disease; ICS: inhaled corticosteroids; LABD: long-acting bronchodilators; BMI: body mass index; FEV1: forced expiratory volume in 1 s; RoW: rest of world. #: China, Indonesia, India, Japan, Korea, Malaysia, Philippines, Taiwan, Thailand and Vietnam; ¶: Austria, Belgium, Bulgaria, Czech Republic, France, Germany, Greece, Hungary, Latvia, Netherlands, Poland, Romania, Slovakia, Spain, UK and Croatia; +: Bosnia and Herzegovina, Belarus, Georgia, Israel, Macedonia (Former Yugoslav Republic of), Russian Federation, Serbia, Turkey and Ukraine; §: Argentina, Australia, Canada, Chile, Columbia, Mexico and South Africa.