TABLE 4

Cox regression analysis of biomarker levels at the 6-week follow-up and associations to 5-year all-cause mortality in 267 hospitalised patients with community-acquired pneumonia

BiomarkerUnivariate analysisMultivariate analysis#
HR (95% CI)p-valueHR (95% CI)p-value
WBCs4.74 (1.89–11.87)0.0012.81 (1.06–7.44)0.037
CRP1.67 (1.34–2.08)<0.0011.29 (0.99–1.67)0.055
PCT2.82 (1.71–4.63)0.0011.73 (0.97–3.09)0.063
Calprotectin2.56 (1.62–4.04)<0.0012.18 (1.27–3.74)0.005
PTX32.31 (1.49–3.59)<0.0011.26 (0.83–1.92)0.282

HR: hazard ratio; WBC: white blood cell; CRP: C-reactive protein; PCT: procalcitonin; PTX3: pentraxin 3. #: adjusted for age, heart failure, active malignant disease, chronic obstructive pulmonary disease and renal disease.